Anaphylaxis

2023 - 3 - 23

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Image courtesy of "Metropolis Healthcare"

Anaphylaxis: Symptoms, Causes, Treatments and Prevention ... (Metropolis Healthcare)

Anaphylaxis is a severe, rare and potentially fatal allergic reaction which requires immediate medical attention otherwise It would be life-threatening.

Epinephrine is the first-line treatment for anaphylaxis, and having an auto-injector in hand can help to prevent a reaction from becoming life-threatening. Food allergies, insect bites, and stings are just two examples of the many things that can cause them. Metropolis Labs offers a reliable and accurate ImmunoCAP™ allergy test to identify allergies and help prevent anaphylaxis. Epinephrine is an emergency injection used to reverse the effects of an anaphylactic reaction. Therefore, educate yourself and your family on the signs of anaphylaxis, its symptoms, and treatments. Corticosteroids reduce inflammation and prevent further damage to the body. Allergies to insect bites and stings can also cause anaphylaxis. Latex allergies are very common and can cause anaphylaxis. Food allergies, for instance, from peanuts, are the most common cause of anaphylaxis. This can be a sign of anaphylactic shock, which is a medical emergency. Anaphylaxis can be a serious condition, so ensuring the person gets the right care and treatment is important. It can involve any body part but is often most severe on the face, back, arms, and legs.

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Image courtesy of "Healio"

Children who skip the ED after anaphylaxis during OIT use ... (Healio)

Most anaphylactic reactions were moderate and occurred during the up-dosing phase of OIT treatment. About half of all patients used antihistamines to treat ...

Among those who did not visit the ED, 18 said two systems were affected, and 13 said three systems were affected. For example, among patients who visited the ED, 12 said two systems were affected, and four said three systems were affected. [treating the anaphylaxis at home](https://www.healio.com/news/allergy-asthma/20221111/most-infants-experiencing-anaphylaxis-receive-epinephrine-few-require-hospitalization), all 12 of those who responded from the ED group said they did so, including nine with epinephrine, six with antihistamines and four with salbuterol. Similarly, those who did not visit the ED included 12 (32.4%) in maintenance and 25 (67.6%) in up-dosing. Additionally, 22 of these children visited an ED, and 37 did not. Further, there were 19 anaphylactic reactions including 13 moderate reactions (68.4%) among those patients who visited the ED and 33 anaphylactic reactions (89.2%) including 24 (72.7%) moderate reactions among those who did not visit the ED. All 37 of the patients who did not visit the ED used epinephrine at home, along 19 who used antihistamines, three who used steroids and 10 who used salbuterol. There also were three allergic reactions among those who visited the ED, including one that was moderate and two that were severe, and four moderate allergic reactions among those who did not visit the ED. Based on the Wilcoxon rank sum test, Gabrielli said, prehospital epinephrine use was significantly higher among the patients who did not present to the ED (P = .001). Specifically, three (13.6%) of the patients who visited the ED were in the maintenance phase, and 19 (86.4%) were in the up-dosing phase. The researchers then used the non-parametric Wilcoxon rank sum test to compare the rates of pre-hospital epinephrine use between the patients who did and did not go to the ED. “We aimed to compare the clinical characteristics and anaphylaxis management between children who are not seen in the ED and children transferred to the ED,” she said.

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